Iran J Pharm Res 2012;11(2):541-8. Am J Clin Dermatol 2010;11(4):247-267. Int Hepatol Comm 1997;233-238. Oh, G. S., Pae, H. O., Oh, H., Hong, S. G., Kim, I. K., Chai, K. Y., Yun, Y. G., Kwon, T. O., and Chung, H. T. In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. Scali, M., Pratesi, C., Zennaro, M. C., Zampollo, V., and Armanini, D. Pseudohyperaldosteronism from liquorice-containing laxatives. Cassano, N., Mantegazza, R., Battaglini, S., Apruzzi, D., Loconsole, F., and Vena, G. A. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. mentioned adverse effects and recurrence rates. Most clinical trials have found that when Peony is combined with Licorice Rt. View abstract. Li J, Fan X, Wang Q. Hypertensive crisis with 2 target organ impairment induced by glycyrrhizin: a case report. Hawrelak, J. The Potential Benefits and Side Effects of the White Peony Root. Gender may affect the action of garlic oil on plasma cholesterol and glucose levels of normal subjects. J Assoc Physicians India 1989;37(10):647. View abstract. Cumming, A. M., Boddy, K., Brown, J. J., Fraser, R., Lever, A. F., Padfield, P. L., and Robertson, J. I. Food Chem Toxicol 1993;31:303-12. View abstract. View abstract. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. Zhong Xi Yi Jie He Za Zhi 1986;6:714-6, 707. Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial. Wilson, J. View abstract. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Little is known about whether it's safe to use licorice root while breastfeeding. View abstract. The combination of Licorice and Peony has been used in TCM for centuries and now used extensively in western herbal medicine for ovarian cysts and PCOS. Guo, D., Ye, G., and Guo, H. A new phenolic glycoside from Paeonia lactiflora. Zhong.Xi.Yi.Jie.He.Za Zhi. Licorice might increase how quickly midazolam is broken down by the body. Warfarin is used to slow blood clotting. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. J Clin Psychopharmacol 2008;28(3):264-370. View abstract. Life Sci 2-23-2001;68(14):1687-1694. Tacconi, P., Paribello, A., Cannas, A., and Marrosu, M. G. Carpal tunnel syndrome triggered by excessive licorice consumption. Fugh-Berman, A. Herb-drug interactions. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. View abstract. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. View abstract. Cochrane Database Syst Rev 2004;4:CD002291. Not too many side effects of peony tea that we need to worry about. View abstract. Arch Pharm Res 2003;26(10):832-839. J Clin Anesth 2019;54:25-32. Baykul, T., Alanoglu, E. G., and Kocer, G. Use of Ankaferd Blood Stopper as a hemostatic agent: a clinical experience. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. 2005;25(6):540-542. Am J Chin Med 1996;24:165-8. 2008;9(3):88-98. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy View abstract. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. I like herbal and fuit teas and a particular favourite of mine contains liquorice. J Ethnopharmacol 2002;81:101-4.. View abstract. Liu J. View abstract. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. Results of a double-blind placebo controlled comparative study]. J Pharmacobiodyn 1984;7:304-11. Mamgain RK, Gupta M, Mamgain P, et al. Lozenge-induced hypermineralcorticoid state--a unique case of licorice lozenges resulting in hypertension and hypokalemia. Yang DG. View abstract. View abstract. View abstract. Amato P, Christophe S, Mellon PL. Pathogenetic considerations and presentation of a clinical case]. Madisch A, Holtmann G, Mayr G, et al. View abstract. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Taking licorice with paclitaxel might decrease the effects of paclitaxel. Br J Clin Pract 1972;26(12):563-566. View abstract. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. View abstract. Eagon PK, Elm MS, Hunter DS, et al. Phytother Res. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Aldosterone is a hormone that causes your body to retain salt (sodium) and lose potassium. Psychoneuroendocrinology. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Rees, W. D., Rhodes, J., Wright, J. E., Stamford, L. F., and Bennett, A. 2020;45(2):257-264. View abstract. Phytother.Res. Medicine (Baltimore) 2018;97(11):e0073. J Peripher.Nerv.Syst. Microbiol Immunol 2000;44(9):799-804. View abstract. Bardhan, K. D., Cumberland, D. C., Dixon, R. A., and Holdsworth, C. D. Clinical trial of deglycyrrhizinised liquorice in gastric ulcer. Contact Dermatitis 1989; 20:152-3.. View abstract. View abstract. 6 Top Celery Juice Benefits & Side Effects. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. Crit Care 2011;15(1):R64. Br J Dermatol 1992;126:179-84. 2011;25(1-2):21-38. View abstract. Taking peony root along with phenytoin might decrease the effects of phenytoin and increase the risk of seizures. View abstract. Licorice or Mulethi, also known as "Sweetwood", is an effective and potent medicinal herb. Serra, A., Uehlinger, D. E., Ferrari, P., Dick, B., Frey, B. M., Frey, F. J., and Vogt, B. Glycyrrhetinic Acid decreases plasma potassium concentrations in patients with anuria. View abstract. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. Kuriyama A, Maeda H. Topical application of licorice for prevention of postoperative sore throat in adults: a systematic review and meta-analysis. J Neuroophthalmol. Roussak NJ. View abstract. The effect of dong quai on menopausal symptoms is unknown. 2007;30(10):1898-1904. Schweiz Med Wochenschr 2-26-1977;107(8):276-279. J Biol Response Mod 1985;4:551-84. Asian Medical Journal 1984;26(7):423-438. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. Kang, D. G., Moon, M. K., Choi, D. H., Lee, J. K., Kwon, T. O., and Lee, H. S. Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. Maeda T, Shinozuka K, Baba K, et al. Harada M, Suzuki M, Ozaki Y. Efficacy and tolerability of hydroalcoholic extract of Paeonia officinalis in children with intractable epilepsy: An open-label pilot study. Luo, Y. G., Liu, Y. Q., and Hu, J. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. View abstract. A., Braun, T. M., and Jacobson, J. J. CJEM 2009;11(1):94-96. J Clin Psychopharmacol 2016;36(6):572-9. BJU Int 2000;85:481-5. Aging Clin Exp Res. View abstract. View abstract. Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Eur J Obstet Gynecol.Reprod Biol 2007;131(1):61-67. View abstract. It shows a wide range of biological and pharmacological activities, including anti-inflammatory and immune regulatory actions. 2020;50:102401. Armanini D, De Palo CB, Mattarello MJ, et al. Lin SH, Yang SS, Chau T, Halperin ML. Koo YK, Kim JM, Koo JY, et al. and Glycyrrhiza glabra L. extracts in patients with Familial Mediterranean Fever. View abstract. Eur J Pharmacol 11-7-2005;524(1-3):111-119. In some cases, this might change the effects and side effects of a medication. Gut 1973;14(9):711-715. Effect of preoperative licorice lozenges on incidence of postextubation cough and sore throat in smokers undergoing general anesthesia and endotracheal intubation. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. View abstract. The roots are commonly used in Traditional Chinese Medicine (TCM) for many purposes. Clin Neurol Neurosurg 1993;95(1):35-37. J Contemp.Dent Pract. Astragalus may be safe when used orally and appropriately. When eaten in large quantities, black licorice can cause serious health issues. Armanini D, Bonanni G, Mattarello MJ, et al. The herb has also been studied for use in canine atopic dermatitis along with white peony (Paeonia lactiflora) and licorice (Glycyrrhiza glabra). View abstract. Gen Dent 2008;56(2):206-210. Hum Exp Toxicol 2012;31(12):1295-1298. Read about Peony uses, side effects, health benefits, interactions, dose, warnings, and precautions. Licorice might decrease how well cisplatin works. Can J Cardiol 2009;25(10):e357-e358. Mechanisms by which Hange-shashin-to reduces prostaglandin E2 levels. View abstract. Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. 2003;84(1):85-89. View abstract. Effect of glycyrrhizin-containing toothpaste on dental plaque reduction and gingival health in humans. Apparent mineralcorticoid excess syndrome, an often forgotten or unrecognized cause of hypokalemia and hypertension: case report and appraisal of the pathophysiology. View abstract. Steinberg, D., Sgan-Cohen, H. D., Stabholz, A., Pizanty, S., Segal, R., and Sela, M. N. The anticariogenic activity of glycyrrhizin: preliminary clinical trials. N Engl J Med 1990;322:849-50. Bannister, B., Ginsburg, R., and Shneerson, J. Cardiac arrest due to liquoriceinduced hypokalaemia. Hsiu, S. L., Lin, Y. T., Wen, K. C., Hou, Y. C., and Chao, P. D. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Clinical and immunological consequences of total glucosides of paeony treatment in Sjgren's syndrome: A randomized controlled pilot trial. Celery juice has become very popular now as it is believed to cure many health problems including obesity, thyroid, gout, blood pressure and fluid retention. Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Davis EA, Morris DJ. Information from this source is evidence-based and objective, and without commercial influence. Eur J Drug Metab Pharmacokinet. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. NOW Supplements, Licorice Root (Glycyrrhiza glabra) 450 mg, Herbal Supplement, 100 Veg Capsules 208. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. View abstract. Peony might slow blood clotting. Sheth, V. M. and Pandya, A. G. Melasma: a comprehensive update: part II. View abstract. Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Am J Epidemiol 2001;153:1085-8. Holtmann G, Madisch A, Juergen H, et al. van der Zwan A. Bai, Y. S., Zhou, C. Y., and Wang, J. Q. Moreover, it will be necessary to check for recurrence . Bian, X., Xu, Y., Zhu, L., Gao, P., Liu, X., Liu, S., Qian, M., Gai, M., Yang, J., and Wu, Y. Report of a new case]. The 54-year-old man was in a fast food . View abstract. Hypertension and the cortisol-cortisone shuttle. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice. Drug Metab Dispos 2015;43(7):1147-53. View abstract. Eriksson JW, Carlberg B, Hillom V. Life-threatening ventricular tachycardia due to liquorice-induced hypokalemia. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. "Water pills" can also decrease potassium levels. Effect of Japanese Angelica root and peony root on uterine contraction in the rabbit in situ. Drug Metab Dispos 2002;30:709-15.. View abstract. An Med Interna 1995;12(1):33-35. View abstract. 2017 Sep;31(9):1330-1340. The effect of Glycyrrhiza glabra L. on primary dysmenorrhea compared with ibuprofen: A randomized, triple-blind controlled trial. Astragalus may interact with medications that suppress the . For women taking oral contraceptives, there is a very small chance that this can counteract the effects of this medication. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid. View abstract. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. All rights reserved. Armanini D, Lewicka S, Pratesi C, et al. The anti-estrogenic action of beta-glycyrrhetinic acid. View abstract. Chin Med J (Engl.) View abstract. Hattori, M., Sakamoto, T., Kobashi, K., and Namba, T. Metabolism of glycyrrhizin by human intestinal flora. Lancet 2000;355(9198):134-138. View abstract. We could use compounds in these foods to . Curr.Pharm.Des 2010;16(26):2935-2947. View abstract. Licorice root extract is often used to relieve symptoms of indigestion, such as acid reflux, upset stomach, and heartburn. 2020 Dec;58(1):352-356. Morris DJ, Davis E, Latif SA. Side effects, toxicity, and interactions. N Engl J Med 1991;325:1223-7. View abstract. Select a condition to view a list of vitamins. View abstract. View abstract. View abstract. View abstract. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. de Klerk GJ, Nieuwenhuis G, Beutler JJ. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Kinoshita, H., Okabayashi, M., Kaneko, M., Yasuda, M., Abe, K., Machida, A., Ohkubo, T., Kamata, T., and Yakushiji, F. Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels. Li C, Wang ZB. Zhang XH, Lowe D, Giles P, et al. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Association of emblica, licorice and belides as an alternative to hydroquinone in the clinical treatment of melasma. View abstract. Brasseur, A. and Ducobu, J. Madisch A, Melderis H, Mayr G, et al. Zhongguo Zhong Xi Yi Jie He Za Zhi. Patients received either bromocriptine 5 mg daily for 4 weeks followed by 4 weeks of 22.5 grams daily of the peony-licorice decoction (equivalent to 25 mg of glycyrrhetinic acid), or the same drugs in the reverse order. View abstract. This information may not fit your specific health circumstances. Isaia, G. C., Pellissetto, C., Ravazzoli, M., and Tamone, C. Acute adrenal crisis and hypercalcemia in a patient assuming high liquorice doses. Costa, A., Moises, T. A., Cordero, T., Alves, C. R., and Marmirori, J. View abstract. Because of its beneficial effects, the licorice root has been dubbed the "Medicinal plant of 2012." Now scientists have discovered that licorice root from the papilionaceae or leguminous family . J Nutr 2001;131:1471-8. View abstract. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. Peters, M. C., Tallman, J. Pharmacol Biochem Behav 1993;45:719-23. . Horm.Res 1999;52(5):253-255. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Contact Dermatitis 2021;85(4):454-455. Ann Clin Biochem 2007;44(Pt 4):397-399. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. Pseudohyperaldosteronism, liquorice, and hypertension. View abstract. Hyodo T, Taira T, Kumakura M, et al. Black licorice can have serious side effects when eaten in large amounts. 2020;2020:8401239. Paeonia lactiflora : Peony is another popular anti-androgenic herb. Vestn.Dermatol.Venerol. Clin Neurol Neurosurg 2003;105:286-7.. View abstract. Some of these health benefits have also . Drugs & Vitamins . Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. Pharm Biol. Aoki, F., Nakagawa, K., Kitano, M., Ikematsu, H., Nakamura, K., Yokota, S., Tominaga, Y., Arai, N., and Mae, T. Clinical safety of licorice flavonoid oil (LFO) and pharmacokinetics of glabridin in healthy humans. Liapina LA, Ammosova IaM, Novikov VS, et al. Features : Herbal Energy & Performance: Bronson's Korean Panax Ginseng provides 1000 MG per serving to naturally support energy and physical performance without any unwanted jitters. Cisplatin is used to treat cancer. View abstract. Some research suggests that licorice extract may help kill bacteria in the mouth that cause tooth decay. View abstract. Dobbins, K. R. and Saul, R. F. Transient visual loss after licorice ingestion. Biol Pharm Bull. Quinkler M, Stewart PM. View abstract. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. No negative side effects. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. View abstract. View abstract. View abstract. Large amounts of licorice can decrease potassium levels in the body. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. Eur J Dermatol. View abstract. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Monograph. 2011;25(2):312-313. therapy. Thom E and Wollan T. A controlled clinical study of kanjang mixture in the treatment of uncomplicated upper respiratory tract infections. Side-effects of low-potassium levels can include lethargy and abnormal heart rhythms. Phytother Res 2006;20(8):687-695. View abstract. View abstract. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. Removes excess melanin: Licorice extract brightens the skin in another way, too. Fitoterapia 2006;77(7-8):613-614. A., Ziaee, A., and Samimi, R. The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. View abstract. [Peony tincture in the complex treatment of allergic dermatoses]. View abstract. View abstract. View abstract. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Total glucosides of peony ameliorates Sjogren's syndrome by affecting Th1/Th2 cytokine balance. View abstract. View abstract. View abstract. . Licorice root contains glycyrrhizin, which can cause side effects when eaten in large amounts. Zheng, A. and Moritani, T. Effect of the combination of ginseng, oriental bezoar and glycyrrhiza on autonomic nervous activity and immune system under mental arithmetic stress. There is only one reminder that peony tea contains caffeine. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. View abstract. Prospective study]. Liang Xiao, Wang YZ, Jing Liu, et al. Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. View abstract. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. J Clin Periodontol 1991;18(3):210-212. View abstract. Traditionally, white peony root is used for treating a wide range of health ailments, like inflammation, pain, and many more. 10. A comparison of carbenoxolone sodium and deglycyrrhizinated liquorice in the treatment of gastric ulcer in the ambulant patient. An Bras Dermatol 2010;85(5):613-620. Read more. View abstract. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Zhang W, Leonard T, Bath-Hextall F, et al. Mol.Nutr Food Res 2011;55(2):318-327. Ha Y, Wang T, Li J, et al. Hattori, T., Ikematsu, S., Koito, A., Matsushita, S., Maeda, Y., Hada, M., Fujimaki, M., and Takatsuki, K. Preliminary evidence for inhibitory effect of glycyrrhizin on HIV replication in patients with AIDS. View abstract. Effect of orally administered shao-yao-gan-cao-tang (Shakuyaku-kanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Tsuda T, Sugaya A, Ohguchi H, et al. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. 1991;4(2):166-173. Asia Pac.J Clin Nutr 2008;17(1):17-22. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. [Clinical observation on auxiliary treatment of hormone dependence dermatitis by shufeng liangxue decoction]. J Clin Psychopharmacol 2008;28(3):264-370. Loop diuretics can also decrease potassium levels. Immunology 1997;90(1):115-120. Planta Med 1983;48(5):38-42. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. 2018;38(2):617-8. View abstract. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. . View abstract. Migraine. Am J Chin Med 1992;20(3-4):313-317. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension.